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IL-4 Antibody

CAT: 0800-F49086-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F49086-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IL4 is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50, Flow Cytometry: 1:10-1:50
UniProt
P05112
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 122-150 from the human protein was used as the immunogen for this IL-4 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, FACS, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the IL-4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This IL-4 antibody is available for research use only.
Storage Conditions
Aliquot the IL-4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the IL-4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Primate
Location
Secreted
Image Legend
(Left) Western blot analysis of IL-4 antibody and WiDr lysate; (Right) Western blot analysis of IL-4 antibody and mouse cerebellum lysate. Expected molecular weight: 14-20 kDa depending on glycosylation level.
Product Datasheet
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