Phospho-IKKB Antibody (pT180) | Gentaur

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Phospho-IKKB Antibody (pT180)

CAT:

800-F48798-0.4ML

Size:

0.4 mL

Price:

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For price, please contact [email protected].

Phospho-IKKB Antibody (pT180)

Description: NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).
UniProt: O14920
Host: Rabbit
Immunogen: This phospho-IKKB antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT180 of human IKKB.
Clonality: Polyclonal
Isotype: Ig
Applications: DB, ELISA
Format: Antigen affinity purified
Buffer: In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution: Aliquot the phospho-IKKB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations: This phospho-IKKB antibody is available for research use only.

Complementary Product Range

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