TSC1 Antibody (phospho-T417)
CAT:
800-F48785-0.08ML
Size:
0.08 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TSC1 Antibody (phospho-T417)
- Description: In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
- CAS Number: 9007-83-4
- UniProt: Q9Z136
- Host: Rabbit
- Immunogen: This phospho-TSC1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT417 of rat TSC1.
- Clonality: Polyclonal
- Isotype: Ig
- Applications: DB, ELISA
- Format: Antigen affinity purified
- Buffer: In 1X PBS, pH 7.4, with 0.09% sodium azide
- Reconstitution: Aliquot the phospho-TSC1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
- Limitations: This phospho-TSC1 antibody is available for research use only.