Phospho-ULK1 Antibody (pS317)

• Description:

  Involved in autophagy. Required for autophagosome formation (By similarity) . Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity) . Phosphorylates ATG13/KIAA0652. Involved in axon growth (By similarity) . Plays an essential role in neurite extension of cerebellar granule cells (By similarity) .

• Specifications:

  Dot blot: 1:500

• UniProt:

  O75385

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This phospho-ULK1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS317 of human ULK1.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  DB, ELISA

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the phospho-ULK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This phospho-ULK1 antibody is available for research use only.

• Storage Conditions:

  Aliquot the phospho-ULK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the phospho-ULK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  Dot blot analysis of phospho-ULK1 antibody. 50ng of phos-peptide or nonphos-peptide per dot were spotted.