Products for Research Use Only
RegisterLogin

Phospho-EGFR Antibody (pS1070)

CAT: 0800-F48516-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-F48516-0.4MLSize:0.4 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma. EGFR is a receptor for EGF, but also for other members of the EGF family, including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation.
CAS Number
9007-83-4
UniProt
P00533
Host
Rabbit
Immunogen
This phospho-EGFR antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS1070 of human EGFR.
Clonality
Polyclonal
Isotype
Ig
Applications
DB, WB, ELISA
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the phospho-EGFR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This phospho-EGFR antibody is available for research use only.

UniProtKB · P00533

Epidermal growth factor receptor

EGFR_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P00533
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
EGFR
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.10.1
Processing
Precursor
Secondary accessions
O00688, O00732, P06268, Q14225, Q68GS5, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneEndoplasmic reticulumEndosomeGolgi apparatusMembraneNucleusSecreted

Molecular function

Developmental proteinHost cell receptor for virus entryKinaseReceptorTransferaseTyrosine-protein kinase

Disease

Disease variantProto-oncogene

PTM

Disulfide bondGlycoproteinHydroxylationIsopeptide bondLipoproteinMethylationPalmitatePhosphoproteinUbl conjugation

Biological process

Host-virus interaction

Domain

RepeatSignalTransmembraneTransmembrane helix
Product Datasheet
Loading...

Related Products

CatalogName
F48516-0.08MLEGFR Antibody (phospho-S1070)
F48553-0.4MLPhospho-EGFR Antibody (pS768)
F48503-0.4MLPhospho-EGFR Antibody (pY998)
RQ4840Phospho-EGFR Antibody (pY1068)
F48552-0.4MLPhospho-EGFR Antibody (pY1016)
F48552-0.08MLEGFR Antibody (phospho-Y1016)
F48508-0.4MLPhospho-EGFR Antibody (pY1172)
RQ4839Phospho-EGFR Antibody (pS695)
F48475-0.08MLEGFR Antibody (phospho-Y1069)
RQ4842Phospho-EGFR Antibody (pY1092)

Alternative Products

CatalogName
abx010691EGFR (pS1070) Antibody
abx328477-01Epidermal Growth Factor Receptor Phospho-Ser1070 (EGFR pS1070) Antibody
MBS460054-01Rabbit anti EGFR (pS1070) Polyclonal Antibody
MBS530440-01phospho EGFR antibody
GTR18338320Phospho-EGFR/EGFR Rabbit Monoclonal Antibody
GTR18304301Phospho-EGFR (Tyr1092) Antibody
GTR18329324-01Phospho-EGFR (Y1125) Antibody
GTR18329301-01Phospho-EGFR (Y998) Antibody
GTR18328211-01Phospho-EGFR (S768) Antibody
GTR18305464Phospho-EGFR (Tyr1173) Antibody

Popular Products