Phospho c-Myc Antibody (pT58)

Phospho c-Myc Antibody (pT58)

• Description: c-Myc participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. This protein appears to activate the transcription of growth-related genes. Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia.
• CAS Number: 9007-83-4
• UniProt: P01106
• Host: Rabbit
• Immunogen: This phospho c-Myc antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT58 of human MYC.
• Clonality: Polyclonal
• Isotype: Ig
• Applications: DB, WB, ELISA
• Format: Antigen affinity purified
• Buffer: In 1X PBS, pH 7.4, with 0.09% sodium azide
• Reconstitution: Aliquot the phospho c-Myc antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
• Limitations: This phospho c-Myc antibody is available for research use only.