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Phospho-MEF2C Antibody (pT20)

CAT: 0800-F48481-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F48481-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. This protein controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. It may also be involved in neurogenesis and in the development of cortical architecture.
CAS Number
9007-83-4
Specifications
Dot blot: 1:500
UniProt
Q06413
Host
Rabbit
Reactivity
Human
Immunogen
This phospho-MEF2C antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT20 of human MEF2C.
Clonality
Polyclonal
Isotype
Ig
Applications
DB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the phospho-MEF2C antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This phospho-MEF2C antibody is available for research use only.
Storage Conditions
Aliquot the phospho-MEF2C antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the phospho-MEF2C antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Bovine, Chicken, Mouse, Pig, Rat, Xenopus
Image Legend
Dot blot analysis of phospho-MEF2C antibody. 50ng of phos-peptide or nonphos-peptide per dot were spotted.

UniProtKB · Q06413

Myocyte-specific enhancer factor 2C

MEF2C_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q06413
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MEF2C
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
C9JMZ0, D7F7N5, F8W7V7
Protein keywords

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

ActivatorDevelopmental proteinDNA-binding

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisDifferentiationNeurogenesisTranscriptionTranscription regulation

Cellular component

CytoplasmNucleus

Disease

Disease variantEpilepsyIntellectual disability

Technical term

Proteomics identificationReference proteome

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