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Phospho-Rb Antibody (pS608)

CAT: 0800-F48443-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F48443-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression occurs in some cases.
CAS Number
9007-83-4
Specifications
Dot blot: 1:500, IHC (Paraffin) : 1:50-1:100
UniProt
P06400
Host
Rabbit
Reactivity
Human
Immunogen
This phospho-Rb antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding phosphorylated S608 of human Rb.
Clonality
Polyclonal
Isotype
Ig
Applications
DB, IHC, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the phospho-Rb antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This phospho-Rb antibody is available for research use only.
Storage Conditions
Aliquot the phospho-Rb antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the phospho-Rb antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Dot blot analysis of phospho-Rb antibody. 50ng of phos-peptide or nonphos-peptide per dot were spotted.

UniProtKB · P06400

Retinoblastoma-associated protein

RB_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P06400
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RB1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K5E3, P78499, Q5VW46, Q8IZL4
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationMethylationPhosphoprotein

Biological process

Cell cycleHost-virus interactionTranscriptionTranscription regulation

Molecular function

Chromatin regulatorDNA-bindingRepressor

Cellular component

CytoplasmNucleus

Disease

Disease variantTumor suppressor
Product Datasheet
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