PHB Antibody / Prohibitin

• Description:

  Prohibitin is an evolutionarily conserved protein that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region.

• Specifications:

  Western blot: 1:1000

• UniProt:

  P35232

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 182-211 from the human protein was used as the immunogen for this PHB antibody.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  WB, ELISA

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the PHB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This PHB antibody is available for research use only.

• Storage Conditions:

  Aliquot the PHB antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the PHB antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• Prediction Reactivity:

  Mouse, Rat, Bovine

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot analysis of PHB antibody and 293 cell lysate either nontransfected (Lane 1) or transiently transfected with the PHB1 gene (2) . Predicted molecular weight ~29 kDa.