Txnip Antibody
CAT:
800-F47779-0.08ML
Size:
0.08 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Txnip Antibody
- Description: May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. [UniProt]
- CAS Number: 9007-83-4
- UniProt: Q8BG60
- Host: Rabbit
- Immunogen: A portion of amino acids 116-145 from the mouse protein was used as the immunogen for this Txnip antibody.
- Clonality: Polyclonal
- Isotype: Ig
- Applications: WB, ELISA
- Format: Antigen affinity purified
- Buffer: In 1X PBS, pH 7.4, with 0.09% sodium azide
- Reconstitution: Aliquot the Txnip antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
- Limitations: This Txnip antibody is available for research use only.