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Sgk1 Antibody

CAT: 0800-F46903-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F46903-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. This enzyme is activated by protein phosphorylation and degraded via the ubiquitination and proteasome pathway. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene was identified on chromosome 12.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
Q9WVC6
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 323-352 from the mouse protein was used as the immunogen for this Sgk1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Sgk1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Sgk1 antibody is available for research use only.
Storage Conditions
Aliquot the Sgk1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Sgk1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Rat
Image Legend
Sgk1 antibody western blot analysis in HeLa lysate.

UniProtKB · Q9WVC6

Serine/threonine-protein kinase Sgk1

SGK1_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q9WVC6
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Sgk1
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
2.7.11.1
Processing
—
Secondary accessions
Q3TJN4, Q3UKD0, Q3UKF2, Q3V1V1, Q6NS85
Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisStress response

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneCytoplasmEndoplasmic reticulumMembraneMitochondrionNucleus

PTM

Disulfide bondPhosphoproteinUbl conjugation

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

Technical term

Reference proteome
Product Datasheet
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