DUSP6 Antibody

CAT: 0800-F45736-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
CAT#:0800-F45736-0.08MLSize:0.08 mL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
Q16828
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 59-88 from the human protein was used as the immunogen for this DUSP6 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the DUSP6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This DUSP6 antibody is available for research use only.
Storage Conditions
Aliquot the DUSP6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the DUSP6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Bovine
Image Legend
DUSP6 antibody western blot analysis in CEM lysate. Predicted molecular weight 42/26 kDa (isoform 1/2) .

Related Products

CatalogName
R33131-100UGDUSP8 Antibody
RQ6126DUSP1 Antibody
R30855DUSP3 Antibody
R33137-100UGDUSP16 Antibody
R36116-100UGDUSP1 Antibody
RQ4624NONO Antibody / p54nrb Antibody
F53954-0.05MLAntibody
F53954-0.2MLAntibody
F53952-0.05MLAntibody
F53952-0.2MLAntibody

Alternative Products

CatalogName
MBS8504769-01DUSP6 Antibody

Popular Products