RHO Antibody / Rhodopsin

• Description:

  Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form, which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness.

• Specifications:

  Western blot: 1:1000

• UniProt:

  P08100

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 310-339 from human Rhodopsin was used as the immunogen for this RHO antibody.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  WB, ELISA

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the RHO antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This RHO antibody is available for research use only.

• Storage Conditions:

  Aliquot the RHO antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the RHO antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• Prediction Reactivity:

  Primate

• CAS Number:

  9007-83-4

• Image Legend:

  RHO antibody western blot analysis in MDA-MB453 lysate. Predicted molecular weight: 40 kDa.