IQGAP1 Antibody

• Description:

  This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.

• Specifications:

  Western blot: 1:1000

• UniProt:

  P46940

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 256-285 from the human protein was used as the immunogen for this IQGAP1 antibody.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  WB, ELISA

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the IQGAP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This IQGAP1 antibody is available for research use only.

• Storage Conditions:

  Aliquot the IQGAP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the IQGAP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  IQGAP1 antibody western blot analysis in T47D lysate. Predicted molecular weight ~189 kDa.