Recoverin Antibody

Recoverin Antibody

• Description: Recoverin belongs to a high-affinity calcium-binding family that includes neuronal calcium sensor-1, visinin-like proteins (VILIPs), guanylate cyclase-activating proteins (GCAPs), and Kv-channel interacting proteins (KchIPs). Features common to this family include four calcium-binding EF-hand domains, and an N-terminal myristoylation sequence. This family of proteins has been implicated in a broad range of cellular signaling functions, including phototransduction and neurotransmitter release, lipid metabolism, gene expression, and ion channel regulation. Myristoylation, the post-translational addition of a fatty acid tail, has been shown to have functional significance for other calcium-binding protein family members. Recoverin is subject to the posttranslational modification of myristoylation. Binding of calcium to recoverin elicits a change in conformation that exposes the buried hydrophobic myristoyl moiety to interaction with cell membranes and other cellular proteins.
• CAS Number: 9007-83-4
• UniProt: P35243
• Host: Rabbit
• Immunogen: A portion of amino acids 169-200 from the human protein was used as the immunogen for this Recoverin antibody.
• Clonality: Polyclonal
• Isotype: Ig
• Applications: WB, IHC, ELISA
• Format: Purified
• Buffer: In 1X PBS, pH 7.4, with 0.09% sodium azide
• Reconstitution: Aliquot the Recoverin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
• Limitations: This Recoverin antibody is available for research use only.