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PAX7 Antibody

CAT: 0800-F44080-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F44080-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50
UniProt
P23759
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 181-210 from the human protein was used as the immunogen for this PAX7 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the PAX7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This PAX7 antibody is available for research use only.
Storage Conditions
Aliquot the PAX7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the PAX7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Mouse
Location
Nuclear
Image Legend
PAX7 antibody western blot analysis in CEM lysate. Expected molecular weight: 55-57 kDa.

UniProtKB · P23759

Paired box protein Pax-7

PAX7_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P23759
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PAX7
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
E9PFV9, Q0VA99, Q2PJS5
Protein keywords

PTM

Acetylation

Coding sequence diversity

Alternative splicingChromosomal rearrangement

Molecular function

Developmental proteinDNA-binding

Disease

Disease variantProto-oncogene

Domain

HomeoboxPaired box

Biological process

MyogenesisTranscriptionTranscription regulation

Cellular component

Nucleus

Technical term

Proteomics identificationReference proteome

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