TP63 Antibody

CAT: 0800-F43397-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
CAT#:0800-F43397-0.08MLSize:0.08 mL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3) ; split-hand/foot malformation 4 (SHFM4) ; ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth) ; limb-mammary syndrome; Rap-Hodgkin syndrome (RHS) ; and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
Q9H3D4
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 651-680 from the human protein was used as the immunogen for this TP63 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the TP63 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This TP63 antibody is available for research use only.
Storage Conditions
Aliquot the TP63 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the TP63 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
TP63 antibody western blot analysis in MDA-MB231 lysate. Predicted molecular weight: 63-77 kDa.

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