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IL-17 Antibody

CAT: 0800-F42568-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F42568-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO) . High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
Q16552
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 61-87 from human IL-17A was used as the immunogen for this IL-17 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the IL-17 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This IL-17 antibody is available for research use only.
Storage Conditions
Aliquot the IL-17 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the IL-17 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Bovine
Image Legend
Western blot analysis of IL-17 antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (2) with the IL17A gene. Expected molecular weight: 15-20 kDa (monomer), 30-40 kDa (homodimer), depending on glycosylation level.
Product Datasheet
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