SETDB1 Antibody

• Description:

  The SET domain is a highly conserved, approximately 150-amino acid motif implicated in the modulation of chromatin structure. It was originally identified as part of a larger conserved region present in the Drosophila Trithorax protein and was subsequently identified in the Drosophila Su (var) 3-9 and 'Enhancer of zeste' proteins, from which the acronym SET is derived. Studies have suggested that the SET domain may be a signature of proteins that modulate transcriptionally active or repressed chromatin states through chromatin remodeling activities.

• Specifications:

  Western blot: 1:1000

• UniProt:

  Q15047

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 1193-1225 from the human protein was used as the immunogen for this SETDB1 antibody.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  WB, ELISA

• Purity:

  Purified

• Format:

  Purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the SETDB1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This SETDB1 antibody is available for research use only.

• Storage Conditions:

  Aliquot the SETDB1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the SETDB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• Prediction Reactivity:

  Mouse, Zebrafish, Xenopus

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot analysis of SETDB1 antibody and Ramos lysate. Predicted molecular weight ~143 kDa (unmodified) and 170-180 kDa (modified) .