IKK beta Antibody

CAT: 0800-F40421-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
CAT#:0800-F40421-0.08MLSize:0.08 mL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine) .
CAS Number
9007-83-4
Specifications
Western blot: 1:100-1:500
UniProt
O14920
Host
Mouse
Reactivity
Human
Immunogen
This IKK beta antibody was raised using purified His-tagged recombinant full length human IKKb.
Clonality
Monoclonal
Isotype
IgG1
Clone
62AT992
Applications
WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the IKK beta antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This IKK beta antibody is available for research use only.
Storage Conditions
Aliquot the IKK beta antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the IKK beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
The IKK beta antibody used in western blot with SK-BR3 cell lysate. Predicted molecular weight ~87 kDa.

Related Products

CatalogName
RQ4722IKK alpha/beta Antibody
F47192-0.4MLIKK Antibody (alpha/beta)
F47192-0.08MLIKK Antibody (alpha/beta)
R30695IKKa Antibody / IKK alpha
R30627IKK gamma Antibody
F40422-0.08MLIKK gamma Antibody
F40422-0.4MLIKK gamma Antibody
R31535IKK alpha Antibody
RQ4721IKK alpha Antibody
F55073-0.2MLChoriogonadotropin beta Antibody / HCG-beta

Alternative Products

CatalogName
abx008721-01Beta Sarcoglycan (beta sarcoglycan) Antibody
GWB-A9A3DDS-100 Antibody (beta-beta)
OAMA01890-1MGS-100 beta-beta Antibody
OAMA01893-1MGS-100 (beta-beta) Antibody
OAMA01891-1MGS-100 beta-beta and alpha-1-beta Antibody
abx345246-01Spectrin beta chain (beta-Spec) Antibody
abx377415-01Beta-Hexosaminidase Subunit Beta (HEXB) Antibody
32183-05111Mouse Interferon beta (IFN-beta) Antibody
MBS9503952-01IL-8R beta/CDw128 beta Antibody
MBS2152732-01Monoclonal Antibody to Beta Catenin (beta-catenin)

Popular Products