PDK4 Antibody

• Description:

  This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.

• Specifications:

  Western blot: 1:100

• UniProt:

  Q16654

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  A purified His-tagged recombinant protein fragment was used to produced this monoclonal PDK4 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG1

• Clone:

  345CT19.6.2

• Applications:

  WB, ELISA

• Purity:

  Purified

• Format:

  Purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the PDK4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This PDK4 antibody is available for research use only.

• Storage Conditions:

  Aliquot the PDK4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the PDK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  PDK4 antibody western blot analysis in K562 lysate. Expected/observed molecular weight ~46 kDa.