KEAP1 Antibody

• Description:

  This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

• Specifications:

  Western blot: 1:100

• UniProt:

  Q14145

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 422-449 from the human protein was used as the immunogen for this KEAP1 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgM k

• Clone:

  297CT6.1.6

• Applications:

  WB, ELISA

• Purity:

  Purified

• Format:

  Purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the KEAP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This KEAP1 antibody is available for research use only.

• Storage Conditions:

  Aliquot the KEAP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the KEAP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• Prediction Reactivity:

  Pig

• CAS Number:

  9007-83-4

• Image Legend:

  KEAP1 antibody western blot analysis in MDA-MB231 lysate. Predicted molecular weight ~70 kDa.