TSC2 Antibody

• Description :

  Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

• Specifications :

  Immunofluorescence: 1:10-1:50, Western blot: 1:100

• UniProt :

  P49815

• Host :

  Mouse

• Reactivity :

  Human, Mouse

• Immunogen :

  This TSC2 antibody was produced from a mouse immunized with TSC2 recombinant protein.

• Clonality :

  Monoclonal

• Isotype :

  IgG1 k

• Clone :

  249CT19.1.3

• Applications :

  WB, IF, ELISA

• Purity :

  Purified

• Format :

  Purified

• Buffer :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution :

  Aliquot the TSC2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations :

  This TSC2 antibody is available for research use only.

• Storage Conditions :

  Aliquot the TSC2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes :

  Titration of the TSC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number :

  9007-83-4

• Image Legend :

  Fluorescent image of HeLa cells stained with TSC2 antibody. Alexa Fluor 488 secondary (green), cytoplasmic actin (red) and nuclei counterstained with DAPI (blue) were used. TSC2 immunoreactivity is localized to the microtubules.