TSC2 Antibody

CAT: 0800-F40275-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
CAT#:0800-F40275-0.4MLSize:0.4 mL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.
CAS Number
9007-83-4
Specifications
Immunofluorescence: 1:10-1:50, Western blot: 1:100
UniProt
P49815
Host
Mouse
Reactivity
Human, Mouse
Immunogen
This TSC2 antibody was produced from a mouse immunized with TSC2 recombinant protein.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
249CT19.1.3
Applications
WB, IF, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the TSC2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This TSC2 antibody is available for research use only.
Storage Conditions
Aliquot the TSC2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the TSC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Fluorescent image of HeLa cells stained with TSC2 antibody. Alexa Fluor 488 secondary (green), cytoplasmic actin (red) and nuclei counterstained with DAPI (blue) were used. TSC2 immunoreactivity is localized to the microtubules.

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