Products for Research Use Only

PAX6 Antibody

CAT: 0800-F40243-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F40243-0.08MLSize:0.08 mL
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Description
This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene. [provided by RefSeq].
CAS Number
9007-83-4
UniProt
P26367
Host
Mouse
Immunogen
This PAX6 antibody was produced from a mouse immunized with PAX6 recombinant protein.
Clonality
Monoclonal
Isotype
IgM κ
Applications
WB, ELISA
Format
Purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the PAX6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This PAX6 antibody is available for research use only.

UniProtKB · P26367

Paired box protein Pax-6

PAX6_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P26367
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PAX6
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q6N006, Q99413
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Molecular function

Developmental proteinDNA-bindingRepressor

Biological process

DifferentiationTranscriptionTranscription regulation

Disease

Disease variantPeters anomaly

Domain

HomeoboxPaired box

Cellular component

Nucleus

PTM

Ubl conjugation
Product Datasheet
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