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CAMK2G Antibody

CAT: 0800-F40148-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F40148-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CaM-kinase II (CAMK2) is a prominent Ser/Thr protein kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Likely autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:50-1:100
UniProt
Q13555
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A portion of amino acids 309-338 from the human protein was used as the immunogen for this CAMK2G antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the CAMK2G antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CAMK2G antibody is available for research use only.
Storage Conditions
Aliquot the CAMK2G antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the CAMK2G antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot of CAMK2G and mouse heart tissue lysate

UniProtKB · Q13555

Calcium/calmodulin-dependent protein kinase type II subunit gamma

KCC2G_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13555
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CAMK2G
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
CaM kinase II subunit gamma, CaMK-II subunit gamma
EC number
2.7.11.17
Processing
—
Secondary accessions
A0A0A0MS52, A0A0A0MT11, O00561, O15378, Q13279, Q13282, Q13556, Q5SQZ3, Q5SQZ4, Q5SWX4, Q7KYX5, Q8N4I3, Q8NIA4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Molecular function

Calmodulin-bindingDevelopmental proteinKinaseSerine/threonine-protein kinaseTransferase

Biological process

DifferentiationNeurogenesis

Disease

Intellectual disability

Cellular component

MembraneSarcoplasmic reticulum

PTM

Phosphoprotein
Product Datasheet
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