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DSCR1 Antibody

CAT: 0800-F40134-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F40134-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DSCR1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. The gene for this protein is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of DSCR1 may lead to neurofibrillary tangles such as those associated with Alzheimer disease.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P53805
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 222-252 from the human protein was used as the immunogen for this DSCR1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the DSCR1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This DSCR1 antibody is available for research use only.
Storage Conditions
Aliquot the DSCR1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the DSCR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Bovine, Hamster, Mouse, Rat
Image Legend
Endothelial cell lysate transferred to membrane was incubated with DSCR1 antibody at a 1:500 dilution. Data courtesy of Dr. Katherine Healey, NWCRF Institute, School of Biological Sciences, University of Wales Bangor.
Product Datasheet
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