NCAPH2 Antibody

CAT: 0800-F40112-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
CAT#:0800-F40112-0.4MLSize:0.4 mL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Structural maintenance of chromosomes (SMC) and non-SMC condensin proteins associate into complexes that have been implicated in the process of chromosome condensation. A crucial prerequisite for accurate segregation of replicated sister chromatids is the condensation of the chromosomes into a manageable form prior to metaphase. The condensin I complex consists of two SMC subunits, SMC2 and SMC4, and three non-SMC subunits, CAP-H, CAP-G, and CAP-D2. An alternative complex, the condensin II complex, contains alternate non-SMC subunits, CAP-G2, CAP-H2, and CAP-D3. CAP-H2 is also known as Non-SMC condensin II complex, subunit H2 (NCAPH2) or kleisin beta isoform 2. The three non-SMC subunits in the condensing complexes form a regulatory subcomplex that is required to activate the SMC ATPases and to promote mitosis-specific chromatin binding of the holocomplex. The precise individual functions of each non-SMC protein in activation remain to be determined.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
Q6IBW4
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 198-227 from the human protein was used as the immunogen for this NCAPH2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the NCAPH2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This NCAPH2 antibody is available for research use only.
Storage Conditions
Aliquot the NCAPH2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the NCAPH2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis of NCAPH2 antibody and HepG2 lysate.
Product Datasheet
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