NCAPH2 Antibody
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
NCAPH2 Antibody
Description :
Structural maintenance of chromosomes (SMC) and non-SMC condensin proteins associate into complexes that have been implicated in the process of chromosome condensation. A crucial prerequisite for accurate segregation of replicated sister chromatids is the condensation of the chromosomes into a manageable form prior to metaphase. The condensin I complex consists of two SMC subunits, SMC2 and SMC4, and three non-SMC subunits, CAP-H, CAP-G, and CAP-D2. An alternative complex, the condensin II complex, contains alternate non-SMC subunits, CAP-G2, CAP-H2, and CAP-D3. CAP-H2 is also known as Non-SMC condensin II complex, subunit H2 (NCAPH2) or kleisin beta isoform 2. The three non-SMC subunits in the condensing complexes form a regulatory subcomplex that is required to activate the SMC ATPases and to promote mitosis-specific chromatin binding of the holocomplex. The precise individual functions of each non-SMC protein in activation remain to be determined.Specifications :
Western blot: 1:1000UniProt :
Q6IBW4Host :
RabbitReactivity :
HumanImmunogen :
A portion of amino acids 198-227 from the human protein was used as the immunogen for this NCAPH2 antibody.Clonality :
PolyclonalIsotype :
IgApplications :
WB, ELISAPurity :
PurifiedFormat :
PurifiedBuffer :
In 1X PBS, pH 7.4, with 0.09% sodium azideReconstitution :
Aliquot the NCAPH2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.Limitations :
This NCAPH2 antibody is available for research use only.Storage Conditions :
Aliquot the NCAPH2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azideApplications Notes :
Titration of the NCAPH2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.CAS Number :
9007-83-4Image Legend :
Western blot analysis of NCAPH2 antibody and HepG2 lysate.
