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(±) -1,2-Propanediol-d2

CAT: 0804-HY-Y0921S1-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-Y0921S1-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(±) -1,2-Propanediol-d2 is the deuterium labeled (±) -1,2-Propanediol. (±) -1,2-Propanediol (1,2- (RS) -Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents[1][2].
CAS Number
58161-11-8
Product Name Alternative
1,2- (RS) -Propanediol-d2; 1,2-Propylene glycol-d2; Propylene glycol-d2
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
Endogenous Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
[2H]OCC(O[2H])C
Molecular Formula
C3H6D2O2
Molecular Weight
78.11
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]De Cock RF, et al. Low but inducible contribution of renal elimination to clearance of propylene glycol in preterm and term neonates. Ther Drug Monit. 2014 Jun;36 (3) :278-87.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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