Adenosine 5'-monophosphate (monohydrate)

Adenosine 5'-monophosphate (monohydrate)

• CAS Number: 18422-05-4
• UNSPSC Description: Adenosine 5'-monophosphate monohydrate is an adenosine A1 receptor agonist. Adenosine 5'-monophosphate monohydrate has significant antiviral activity against HSV-1 and HSV-2.
• Target Antigen: Adenosine Receptor; Endogenous Metabolite; HSV
• Type: Natural Products
• Related Pathways: Anti-infection;GPCR/G Protein;Metabolic Enzyme/Protease
• Applications: Neuroscience-Neuromodulation
• Field of Research: Infection; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/adenosine-5-monophosphate-monohydrate.html
• Purity: 99.07
• Solubility: H2O : 5 mg/mL (ultrasonic;warming)
• Smiles: O[C@@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]1N2C=NC3=C2N=CN=C3N.O
• Molecular Weight: 365.24
• References & Citations: [1]Rittiner JE, et al. AMP is an adenosine A1 receptor agonist. J Biol Chem. 2012 Feb 17;287(8):5301-9.|[2]Zhan Y, et al. Adenosine 5'-monophosphate ameliorates D-galactosamine/lipopolysaccharide-induced liver injury through an adenosine receptor-independent mechanism in mice. Cell Death Dis. 2014 Jan 9;5:e985.|[3]Ayisi NK, et al. Comparison of the antiviral effects of 5-methoxymethyldeoxyuridine-5'-monophosphate with adenine arabinoside-5'-monophosphate. Antiviral Res. 1983 Sep;3(3):161-74.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: Launched