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CycFWRPW

CAT: 0804-HY-P10488Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P10488Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CycFWRPW is a peptide inhibitor of TLE1. TLE1 is an oncogenic transcriptional co‐repressor that exerts its repressive effects through binding of transcription factors, and inhibits Wnt signaling[1].
CAS Number
2116533-34-5
UNSPSC
12352209
Target
Others; Wnt
Type
Peptides
Related Pathways
Others; Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cycfwrpw.html
Smiles
O=C(N[C@@H](CC1=CNC2=C1C=CC=C2)C(O)=O)[C@@]3(CCCN3C([C@@H](NC([C@@H](NC([C@@H](N)CC4=CC=CC=C4)=O)C5)=O)CCCNC(N)=N)=O)CCCCN6C=C5C7=C6C=CC=C7
Molecular Formula
C46H56N10O6
Molecular Weight
845.00
References & Citations
[1]McGrath S, et al. Structure-Enabled Discovery of a Stapled Peptide Inhibitor to Target the Oncogenic Transcriptional Repressor TLE1. Chemistry. 2017 Jul 18;23 (40) :9577-9584.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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CatalogName
GTR19063654-01CycFWRPW

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