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4'-Methylchrysoeriol

CAT: 0804-HY-112734-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-112734-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
4'-Methylchrysoeriol is a potent inhibitor of Cytochrome P450 enzymes, with an IC50 of 19 nM for human P450 1B1-dependent EROD.
CAS Number
4712-12-3
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/4_acute_-Methylchrysoeriol.html
Purity
99.17
Solubility
DMSO : 20.83 mg/mL (ultrasonic)
Smiles
O=C1C=C(C2=CC=C(OC)C(OC)=C2)OC3=CC(O)=CC(O)=C13
Molecular Formula
C17H14O6
Molecular Weight
314.29
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Shimada T, et al. Reverse type I binding spectra of human cytochrome P450 1B1 induced by flavonoid, stilbene, pyrene, naphthalene, phenanthrene, and biphenyl derivatives that inhibit catalytic activity: a structure-function relationship study. Chem Res Toxicol. 2009 Jul;22 (7) :1325-33.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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