Poloxamer 181 (L61)

• UNSPSC Description:

  Poloxamer 181 L61 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2000. Poloxamer 181 L61 exhibits antimicrobial activity, that inihibits 91% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 181 L61 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering[1][2].

• Target Antigen:

  Bacterial; Biochemical Assay Reagents

• Type:

  Biochemical Assay Reagents

• Related Pathways:

  Anti-infection;Others

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/poloxamer-181-l61.html

• Solubility:

  10 mM in DMSO

• Smiles:

  [Poloxamer 181 (L61)]

• Molecular Weight:

  2000 (Average)

• References & Citations:

  [1]Singh-Joy SD, et al., Safety assessment of poloxamers 101, 105, 108, 122, 123, 124, 181, 182, 183, 184, 185, 188, 212, 215, 217, 231, 234, 235, 237, 238, 282, 284, 288, 331, 333, 334, 335, 338, 401, 402, 403, and 407, poloxamer 105 benzoate, and poloxamer 182 dibenzoate as used in cosmetics. Int J Toxicol. 2008;27 Suppl 2:93-128.|[2]Hunter RL, et al., Enhancement of antibiotic susceptibility and suppression of Mycobacterium avium complex growth by poloxamer 331. antimicrob Agents Chemother. 1995 Feb;39(2):435-9.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9003-11-6