PqsR/LasR-IN-1

PqsR/LasR-IN-1

• CAS Number: 924818-33-7
• UNSPSC Description: PqsR/LasR-IN-1 (compound 2a) is a potent PqsR and LasR systems inhibitor. PqsR/LasR-IN-1 has anti-virulence activity against Pseudomonas aeruginosa. PqsR/LasR-IN-1 can reduce production of biofilm, pyocyanin, and rhamnolipids in PA[1].
• Target Antigen: Antibiotic; Bacterial
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/pqsr-lasr-in-1.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: CC1=C(C=C(C=C1)NC(C2=CC3=C(C(OC(C3)C4=CC=C(C=C4)Cl)=O)C=C2)=O)C
• Molecular Weight: 405.87
• References & Citations: [1]Mohammad Anwar Hossain, et al. Design, synthesis, and evaluation of compounds capable of reducing Pseudomonas aeruginosa virulence. Eur J Med Chem. 2020 Jan 1;185:111800.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported