AHN 1-055 (hydrochloride)

AHN 1-055 (hydrochloride)

• CAS Number: 202646-03-5
• UNSPSC Description: AHN 1-055 hydrochloride is a dopamine uptake inhibitor, with an IC50 of 71 nM. AHN 1-055 hydrochloride binds with high affinity to the dopamine transporter (DAT)[1].
• Target Antigen: Dopamine Transporter
• Type: Reference compound
• Related Pathways: Neuronal Signaling
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/ahn-1-055-hydrochloride.html
• Purity: 99.96
• Solubility: DMSO : 100 mg/mL (ultrasonic)|H2O : 33.33 mg/mL (ultrasonic)
• Smiles: CN1[C@@H]2C[C@@H](OC(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)C[C@H]1CC2.Cl
• Molecular Weight: 379.87
• References & Citations: [1]Sangeeta R, et, al. Investigation of the potential pharmacokinetic and pharmaco-dynamic drug interaction between AHN 1-055, a potent benztropine analog used for cocaine abuse, and cocaine after dosing in rats using intracerebral microdialysis. Biopharm Drug Dispos. 2006 Jul; 27(5): 229-40.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported