Quin C1

• Description :

  Quin C1 is a highly specific and potent agonist for formyl peptide receptor 2 (FPR2/ALX) . Quin-C1 significantly reduces the neutrophil and lymphocyte counts in BALF, diminishes expression of TNF-α, IL-1β, KC, and TGF-β1, and decreases collagen deposition in lung tissue. Quin C1 has the potential for the research of lung injury[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H315-H319-H320

• Target :

  Formyl Peptide Receptor (FPR)

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/quin-c1.html

• Purity :

  98.47

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(C1=CC=C(OCCCC)C=C1)NN2C(C3=CC=C(OC)C=C3)NC4=CC=CC=C4C2=O

• Molecular Formula :

  C26H27N3O4

• Molecular Weight :

  445.51

• Precautions :

  P264-P280-P302+P352-P305+P351+P338-P362

• References & Citations :

  [1]He M, et al. Characterization of Quin-C1 for its anti-inflammatory property in a mouse model of bleomycin-induced lung injury. Acta Pharmacol Sin. 2011;32 (5) :601-610.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [786706-21-6]