Quin C1

CAT: 0804-HY-110246-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-110246-01Size:5 mg
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Description
Quin C1 is a highly specific and potent agonist for formyl peptide receptor 2 (FPR2/ALX) . Quin-C1 significantly reduces the neutrophil and lymphocyte counts in BALF, diminishes expression of TNF-α, IL-1β, KC, and TGF-β1, and decreases collagen deposition in lung tissue. Quin C1 has the potential for the research of lung injury[1].
CAS Number
[786706-21-6]
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Formyl Peptide Receptor (FPR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/quin-c1.html
Purity
98.47
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(OCCCC)C=C1)NN2C(C3=CC=C(OC)C=C3)NC4=CC=CC=C4C2=O
Molecular Formula
C26H27N3O4
Molecular Weight
445.51
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]He M, et al. Characterization of Quin-C1 for its anti-inflammatory property in a mouse model of bleomycin-induced lung injury. Acta Pharmacol Sin. 2011;32 (5) :601-610.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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