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Meclonazepam

CAT: 0804-HY-101725-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-101725-01Size:5 mg
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Description
Meclonazepam (Ro 11-3128) is a benzodiazepine compound with anxiolytic effect[1]. Meclonazepam is active against immature S. mansoni. Meclonazepam (30 μM) eliminates 100% of immature parasites. Meclonazepam has a anti-schistosomal effect[2].
CAS Number
58662-84-3
Product Name Alternative
Ro 11-3128; Ro 11-3128/002
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/meclonazepam.html
Concentration
10mM
Purity
99.97
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1NC2=CC=C([N+]([O-])=O)C=C2C(C3=CC=CC=C3Cl)=N[C@H]1C
Molecular Formula
C16H12ClN3O3
Molecular Weight
329.74
Precautions
H302, H315, H319, H335
References & Citations
[1]T U Järbe, et al. Cueing effects of anxiolytic benzodiazepines (DZP and Ro 11-3128) : stereospecificity and antagonism by the convulsant benzodiazepine Ro 5-3663. Psychopharmacology (Berl) . 1988;94 (4) :501-6.|[2]L Pica-Mattoccia, et al. Praziquantel and the benzodiazepine Ro 11-3128 do not compete for the same binding sites in schistosomes. Parasitology. 2008 Jan;135 (Pt 1) :47-54.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Schistosome