2-Deoxy-D-glucose 6-phosphate (disodium)

2-Deoxy-D-glucose 6-phosphate (disodium)

• CAS Number: 33068-19-8
• UNSPSC Description: 2-Deoxy-D-glucose 6-phosphate disodium, a derivative of 2-Deoxy-D-glucose, is produced in mammalian cells by the action of hexokinase on 2-DG. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/2-deoxy-d-glucose-6-phosphate-disodium.html
• Smiles: O=P(O[Na])(O[Na])OC[C@@H](O)[C@@H](O)[C@H](O)CC=O
• Molecular Weight: 288.10
• References & Citations: [1]Zhu Z, et al. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res. 2005 Aug 1;65(15):7023-30.|[2]B Pajak, et al. 2-Deoxy-d-Glucose and Its Analogs: From Diagnostic to Therapeutic Agents. Int J Mol Sci. 2019 Dec 29;21(1):234.
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