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β-D-Galactose pentaacetate

CAT: 0804-HY-W039923-01Size: 25 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W039923-01Size:25 g
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Description
β-D-Galactose pentaacetate is a negative regulator of insulin with plasma membrane penetrating ability and can be hydrolyzed by intracellular esterases. β-D-Galactose pentaacetate inhibits Leucine -induced insulin release in Wistar rat islets, potentially preventing excessive insulin release in pathological conditions[1][2][3].
CAS Number
4163-60-4
UNSPSC
12352200
Hazard Statement
H302, H315, H319, H335
Target
Insulin Receptor
Type
Biochemical Assay Reagents
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/β-d-galactose-pentaacetate.html
Purity
99.86
Solubility
DMSO : 100 mg/mL (ultrasonic) |Methanol : 16.67 mg/mL (ultrasonic)
Smiles
CC(O[C@H]1[C@H]([C@H](O[C@H]([C@@H]1OC(C)=O)OC(C)=O)COC(C)=O)OC(C)=O)=O
Molecular Formula
C16H22O11
Molecular Weight
390.34
Precautions
H302, H315, H319, H335
References & Citations
[1]Malaisse WJ, et al. Inhibition of insulin release by alpha- and beta-D-galactose pentaacetate. Int J Mol Med. 1998 Sep;2 (3) :331-2.|[2]Malaisse WJ, et al. Insulinotropic action of beta-L-glucose pentaacetate. Am J Physiol. 1998 Dec;275 (6) :E993-E1006.|[3]Kadiata MM, Malaisse WJ. Opposite effects of D-glucose pentaacetate and D-galactose pentaacetate anomers on insulin release evoked by succinic acid dimethyl ester in rat pancreatic islets. Life Sci. 1999;64 (9) :751-4.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported

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