Amthamine

• Description:

  Amthamine is a histamine receptor (H1R-H4R) agonist. Amthamine can produce liver congestion and necrosis of liver cells. Amthamine can be used to study the induction effect of H1R-H4 agonist on hepatotoxicity [1].

• UNSPSC:

  12352005

• Hazard Statement:

  H315-H319-H320

• Target:

  Histamine Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/amthamine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  NCCC1=C(C)N=C(N)S1

• Molecular Formula:

  C6H11N3S

• Molecular Weight:

  157.24

• Precautions:

  P264-P280-P302+P352-P305+P351+P338-P362

• References & Citations:

  [1]Trivendra Tripathi, et al. Hepatotoxicity Due to Histamine Trifluoro-Methyl Toluidide, Amthamine, R- (-) -α-Methyl Histamine and Clobenpropit (H1R-H4R-Agonists, Respectively) in Rabbit Experimental Model. American Medical Journal. 2010, 1 (1) : 1-7.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [142437-67-0]