Sugiol

• UNSPSC Description:

  Sugiol is an abietane diterpenoid, can be isolated from Calocedrus formosana bark. Sugiol has anti-inflammatory activity, could effectively reduce intracellular reactive oxygen species (ROS) production in lipopolysaccharide (LPS)-stimulated macrophages[1].

• Target Antigen:

  ERK; Interleukin Related; JNK; p38 MAPK; TNF Receptor

• Type:

  Natural Products

• Related Pathways:

  Apoptosis;Immunology/Inflammation;MAPK/ERK Pathway;Stem Cell/Wnt

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/sugiol.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C2=C(C=C(O)C(C(C)C)=C2)[C@@]3(C)CCCC(C)(C)[C@]3([H])C1

• Molecular Weight:

  300.44

• References & Citations:

  [1]Chao KP, et al. Anti-inflammatory activity of sugiol, a diterpene isolated from Calocedrus formosana bark. Planta Med. 2005 Apr;71(4):300-5.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  511-05-7