YHIEPV

CAT: 0804-HY-P10397-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-P10397-01Size:5 mg

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Description

YHIEPV (rALP-2, Rubisco anxiolytic-like peptide 2) is a potent and orally active peptide. YHIEPV shows anxiolytic effects. YHIEPV increases leptin sensitivity to exert its anti-obesity effects[1][2].

CAS Number

2243939-21-9

Product Name Alternative

RALP-2, Rubisco anxiolytic-like peptide 2

UNSPSC

12352209

Target

IGluR

Type

Peptides

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/yhiepv.html

Purity

99.85

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N[C@@H](CC1=CNC=N1)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(O)=O)C(N2[C@@H](CCC2)C(N[C@@H](C(C)C)C(O)=O)=O)=O)=O)=O)[C@H](CC3=CC=C(C=C3)O)N

Molecular Formula

C36H52N8O10

Molecular Weight

756.85

References & Citations

[1]Kimura S, et al. Identification of Rubisco anxiolytic-like peptides (rALPs) by comprehensive analysis of spinach green leaf protein digest. Biochem Biophys Res Commun. 2018 Nov 10;505 (4) :1050-1056.|[2]Kaneko K, et al. An orally active plant Rubisco-derived peptide increases neuronal leptin responsiveness. Sci Rep. 2022 May 21;12 (1) :8599.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Chemical Information

Yhiepv

CAS Number	2243939-21-9
PubChem CID	171714354
IUPAC Name	(4S)-4-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-methylpentanoyl]amino]-5-[(2S)-2-[[(1S)-1-carboxy-2-methylpropyl]carbamoyl]pyrrolidin-1-yl]-5-oxopentanoic acid
Molecular Formula	C36H52N8O10
Molecular Weight	756.8
XLogP	-1.2
Topological Polar Surface Area	286
Hydrogen Bond Donor Count	9
Hydrogen Bond Acceptor Count	12
Rotatable Bond Count	20
Heavy Atom Count	54
Formal Charge	0
Complexity	1330

SMILES

CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)[C@H](CC2=CN=CN2)NC(=O)[C@H](CC3=CC=C(C=C3)O)N

InChI

InChI=1S/C36H52N8O10/c1-5-20(4)30(43-32(49)26(16-22-17-38-18-39-22)41-31(48)24(37)15-21-8-10-23(45)11-9-21)34(51)40-25(12-13-28(46)47)35(52)44-14-6-7-27(44)33(50)42-29(19(2)3)36(53)54/h8-11,17-20,24-27,29-30,45H,5-7,12-16,37H2,1-4H3,(H,38,39)(H,40,51)(H,41,48)(H,42,50)(H,43,49)(H,46,47)(H,53,54)/t20-,24-,25-,26-,27-,29-,30-/m0/s1

InChIKey

MPORDPMEKCNCRM-XHJIKMKMSA-N

Chemical Structure

2D Structure

CAS: 2243939-21-9

CID: 171714354

Formula: C36H52N8O10

MW: 756.8

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	756.8
XLogP3	-1.2
Hydrogen Bond Donor Count	9
Hydrogen Bond Acceptor Count	12
Rotatable Bond Count	20
Exact Mass	756.38063989
Monoisotopic Mass	756.38063989
Topological Polar Surface Area	286 Å²
Heavy Atom Count	54
Formal Charge	0
Complexity	1330
Isotope Atom Count	0
Defined Atom Stereocenter Count	7
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
GTR19062939-01	YHIEPV

YHIEPV

Chemical Information

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