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R8605

CAT: 0804-HY-120463Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120463Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
R8605 is an inhibitor for PKC with an IC50 of 65 μM for PKC in rat brain. R8605 inhibits calcium/phospholipid-independent phosphorylation of protamine with IC50 of 70 μM and 100 μM. R8605 can be used in cancer research[1].
CAS Number
119306-51-3
UNSPSC
12352005
Target
PKC
Type
Reference compound
Related Pathways
Epigenetics; TGF-beta/Smad
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r8605.html
Smiles
O=C(O)C1=CC=C(NC(C2=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C2)=O)C=C1
Molecular Formula
C22H27NO4
Molecular Weight
369.45
References & Citations
[1]Sun S. The inhibitory effect of a third generation retinoid, R8605, on protein kinase C activity in vitro[J]. Zhongguo yi xue ke xue Yuan xue bao. Acta Academiae Medicinae Sinicae, 1991, 13 (4) : 267-270.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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