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NO-711

CAT: 0804-HY-114040Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-114040Size:1 Each
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Description
NO-711 (NNC-711) free acid is a novel potent and selective inhibitor of γ-aminobutyric acid uptake. NO-711 inhibits synaptosomal (IC50 = 47 nM), neuronal (IC50 = 1238 nM) and glial (IC50 = 636 nM) GABA uptake in vitro[1].
CAS Number
159094-94-7
Product Name Alternative
NNC-711 (free acid)
UNSPSC
12352005
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/no-711.html
Smiles
O=C(C1=CCCN(CCO/N=C(C2=CC=CC=C2)\C3=CC=CC=C3)C1)O
Molecular Formula
C21H22N2O3
Molecular Weight
350.41
References & Citations
[1]P D Suzdak, et al. NNC-711, a novel potent and selective gamma-aminobutyric acid uptake inhibitor: pharmacological characterization. Eur J Pharmacol. 1992 Dec 2;224 (2-3) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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