Divaplon

CAT: 0804-HY-19438-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-19438-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Divaplon is a GABA receptor agonist with the EC50 values of 31 and 2 nM for α3β2γ2 and α5β2γ2, respectively. Divaplon shows anxiolytic activity[1][2].

CAS Number

90808-12-1

Product Name Alternative

RU 32698

UNSPSC

12352005

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/divaplon.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CN2C(C)=C(CC)C(OC)=NC2=N1)C3=CC=CC=C3

Molecular Formula

C17H17N3O2

Molecular Weight

295.34

References & Citations

[1]Knoflach F, et al. Full and partial agonism displayed by benzodiazepine receptor ligands at recombinant gamma-aminobutyric acidA receptor subtypes. J Pharmacol Exp Ther. 1993;266 (1) :385-391. |[2]Sanger DJ, et al. Benzodiazepine (omega) receptor partial agonists and the acquisition of conditioned fear in mice. Psychopharmacology (Berl) . 1995;121 (1) :104-108.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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T27186-01	Divaplon

Divaplon

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