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HMGB1 (AcK12) polyclonal antibody

CAT: 0013-GTR18213358-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0013-GTR18213358-01Size:50 μL
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Description
HMGB1 (AcK12) polyclonal antibody
Product Name Alternative
HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1
UniProt
P09429
Reactivity
Human, Mouse, Rat
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human HMGB1 (AcK12) . The exact sequence is proprietary.
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Autophagic, Cancer, DNA Damage, Epigenetics, Immunology, Infectious Diseases, Neuroscience, Signaling Pathways
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 218% (by SDS-PAGE) .
Concentration
1mg/ml
Dilution
WB (1/500 - 1/1000)
Form
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Molecular Weight
~ 90 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

UniProtKB · P09429

High mobility group protein B1

HMGB1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P09429
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HMGB1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A5D8W9, Q14321, Q5T7C3, Q6IBE1
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationADP-ribosylationDisulfide bondIsopeptide bondOxidationPhosphoprotein

Biological process

Adaptive immunityAutophagyChemotaxisDNA damageDNA recombinationDNA repairHost-virus interactionImmunityInflammatory responseInnate immunity

Cellular component

Cell membraneChromosomeCytoplasmEndoplasmic reticulumEndosomeMembraneNucleusSecreted

Molecular function

DNA-binding

Domain

Repeat

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