Kemptide

• Description :

  Kemptide is a synthetic heptapeptide that acts as a specific substrate for cAMP-dependent protein kinase (PKA) .

• CAS Number :

  [65189-71-1]

• UNSPSC :

  12352209

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  PKA

• Type :

  Peptides

• Related Pathways :

  Stem Cell/Wnt; TGF-beta/Smad

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/Kemptide.html

• Purity :

  98.9

• Solubility :

  H2O : ≥ 100 mg/mL

• Smiles :

  O=C(O)CNC([C@H](CC(C)C)NC([C@H](CO)NC([C@H](C)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)N)=O)=O)=O)=O)=O)=O

• Molecular Formula :

  C32H61N13O9

• Molecular Weight :

  771.91

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Kübler D, et al. Evidence for ecto-protein kinase activity that phosphorylates Kemptide in a cyclic AMP-dependent mode. J Biol Chem. 1989 Aug 25;264 (24) :14549-55.|[2]Duncan FE, et al. Transducin-like enhancer of split-6 (TLE6) is a substrate of protein kinase A activity during mouse oocyte maturation. Biol Reprod. 2014 Mar 20;90 (3) :63.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported