Products for Research Use Only
RegisterLogin

YZL-51N

CAT: 0804-HY-159124-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-159124-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
YZL-51N is a selective SIRT7 inhibitor with IC50 value of 12.71 μM. YZL-51N disrupts SIRT7 enzyme activity by occupying the NAD+ binding pocket, thereby weakening DNA damage repair and inhibiting cancer cell survival. YZL-51N possesses anti-tumor activity and can be used in cancer research[1].
CAS Number
3031072-69-9
UNSPSC
12352005
Target
Sirtuin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/yzl-51n.html
Purity
95.0
Solubility
DMSO : 33.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(OC)/C(C1=CC=C(O)C(O)=C1)=C\C(C2=CC=C(O)C(O)=C2)=O
Molecular Formula
C17H14O7
Molecular Weight
330.29
References & Citations
[1]Kang TS, et al. YZL-51N functions as a selective inhibitor of SIRT7 by NAD+ competition to impede DNA damage repair. iScience. 2024 May 16;27 (6) :110014.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SIRT7

Alternative Products

CatalogName
T89271-01YZL-51N

Popular Products