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EGR2 (C) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18212218Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18212218Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to EGR2. E3 SUMO-protein ligase EGR2 belongs to the EGR C2H2-type zinc-finger protein family. EGR2 is a sequence-specific DNA-binding transcription factor and binds to two specific DNA sites located in the promoter region of HOXA4. EGR2 helps SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity. Defects in EGR2 are a cause of congenital hypomyelination neuropathy (CHN), of Charcot-Marie-Tooth disease type 1D (CMT1D), and of Dejerine-Sottas syndrome (DSS) .
Product Name Alternative
Anti E3 SUMO-protein ligase EGR2 antibody, anti AT591 antibody, anti Early growth response protein 2 antibody, anti Zinc finger protein Krox-20 antibody, anti EGR-2 antibody, anti KROX20 antibody
UniProt
P11161
Reactivity
Human, Mouse
Immunogen
C-terminal region of human EGR2
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Neuroscience
Concentration
100 μg/ml BSA
Dilution
WB:1:1000-1:3000, IF/ICC:1:100-1:200
Purity
Affinity purification
Molecular Weight
50
References & Citations
Chengyun Xu et al. Early growth response 2 as a target of IL-13/STAT6 signaling induces the goblet cell metaplasia of allergic airway epithelia Allergol Int, (2026)
Pubmed id
41708397
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human EGR2.
Tested Applications
ChIP, IP, WB
Host or Source
Rabbit
Preservative
0.01% NaN3

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