Products for Research Use Only

DDX17 (N) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18212144Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18212144Size:100 µL
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Description
Rabbit polyclonal to DDX17. Probable ATP-dependent RNA helicase DDX17 belongs to the DEAD box helicase family and the DDX5/DBP2 subfamily. DDX17 is an RNA-dependent ATPase activity. DDX17 is involved in transcriptional regulation and is a transcriptional coactivator for estrogen receptor ESR1. DDX17 increases ESR1 AF-1 domain-mediated transactivation. Additionally, DDX17 synergizes with DDX5 and SRA1 RNA to activate MYOD1 transcriptional activity and is probably involved in skeletal muscle differentiation. Furthermore, DDX17 is required for zinc-finger antiviral protein ZC3HAV1-mediated mRNA degradation.
Product Name Alternative
Anti Probable ATP-dependent RNA helicase DDX17 antibody, anti DEAD box protein 17 antibody, anti DEAD box protein p72 antibody, anti RNAdependent helicase p72 antibody
UniProt
Q92841
Reactivity
Human, Mouse
Immunogen
N-terminal region of human DDX17
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Infectious Disease & Virology
Concentration
100 μg/ml BSA
Dilution
WB:1:1000-1:3000
Purity
Affinity purification
Molecular Weight
80
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human DDX17.
Tested Applications
IP, WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · Q92841

Probable ATP-dependent RNA helicase DDX17

DDX17_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q92841
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DDX17
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.6.4.13
Processing
—
Secondary accessions
B1AHM0, H3BLZ8, Q69YT1, Q6ICD6
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondMethylationPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative initiationAlternative splicing

Biological process

Antiviral defenseImmunitymRNA processingmRNA splicingRNA-mediated gene silencingrRNA processingTranscriptionTranscription regulation

Ligand

ATP-bindingNucleotide-binding

Cellular component

CytoplasmNucleus

Molecular function

HelicaseHydrolaseRNA-binding