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TFAP2B (N1) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18212099Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18212099Size:100 µL
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Description
Rabbit polyclonal to TFAP2B. Transcription factor AP-2-beta (TFAP2B) belongs to the AP-2 family and is a sequence-specific DNAbinding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5-GCCNNNGGC-3 and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.
Product Name Alternative
Anti Transcription factor AP-2-beta antibody, anti AP2-beta antibody, anti Activating enhancer-binding protein 2-beta antibody
UniProt
Q92481
Reactivity
Human, Mouse
Immunogen
N-terminal region of human TFAP2B
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics
Concentration
100 μg/ml BSA
Dilution
WB:1:1000-1:3000
Purity
Affinity purification
Molecular Weight
50
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human TFAP2B.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

UniProtKB · Q92481

Transcription factor AP-2-beta

AP2B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q92481
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TFAP2B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
AP2-beta
EC number
—
Processing
—
Secondary accessions
Q5JYX6, Q9NQ63, Q9NU99, Q9UJI7, Q9Y214, Q9Y3K3
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorDNA-binding

Coding sequence diversity

Alternative splicing

Disease

Disease variant

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Cellular component

Nucleus

Biological process

TranscriptionTranscription regulation

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